Research Fellow in Molecular Biology with a Focus on Aging and Metabolism
Job Summary:
The Manstein Laboratory at Massachusetts General Hospital is conducting research in dermatology, focusing on the development of novel, energy-based procedures for the treatment of various skin conditions, including scars, burns, aging, and fat removal. We are expanding our research scope to include the molecular mechanisms underlying aging, energy homeostasis, adipogenesis, and the biochemical basis of metabolic diseases. We seek a Research Fellow with a strong background in Molecular Biology and Immunology, specifically with expertise in aging, energy balance, tissue development, and the pathogenesis of metabolic diseases, including obesity. This role involves designing and conducting experiments, analyzing data, and contributing to our understanding of these conditions to identify novel therapeutic targets.
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Preferred Qualifications:
Position Details:
This is a full-time role offering a competitive salary (above NIH post doc stipend levels) and benefits package, matching experience, and qualifications. Located within the research community of Massachusetts General Hospital/Harvard Medical School, the Manstein Lab provides an exceptional environment for scientific growth and discovery.
Candidates passionate about advancing the field of molecular biology with a focus on aging, energy homeostasis, and metabolic diseases and eager to contribute to the development of medical solutions are encouraged to apply. Please submit your application, including a resume and a cover letter outlining your relevant experiences and interests.
Applications will be reviewed on a rolling basis until the position is filled. We thank all applicants for their interest; however, only those selected for an interview will be contacted.
Project Description:
Building on our findings with large area fractional laser treatment (LAFLT) and its significant metabolic effects, our next project aims to deepen our understanding by exploring the broader molecular and systemic impacts of LAFLT, with a particular focus on aging and energy homeostasis. This research will extend beyond the metabolic parameters to investigate how LAFLT influences aging processes, modulating energy homeostasis and the immune response at a cellular level to potentially improve tissue function and longevity. By integrating various advanced molecular techniques and systemic analyses, including gene expression profiling, epigenetic markers of aging, and assessments of mitochondrial function, we will elucidate the mechanisms through which LAFLT affects not only metabolism but also the broader physiological landscape. This project promises to uncover novel insights into the potential of LAFLT as a multifaceted therapeutic approach, potentially offering new avenues for treating aging-related diseases, optimizing energy balance, and enhancing overall health.
Previous Publications:
https://www.sciencedirect.com/science/article/pii/S2589004223027542
Requirements:
Preferred Qualifications: