The primary purpose of this position is to support ongoing research in understanding Alzheimer's disease (AD) and to help develop experiments to test potential treatments for AD and other neurological diseases. This position requires an ability to work well independently as well as work closely with a team. Hours are flexible but this position does require some weekend work.

Job Duties/Responsibilities:
50% Design, plan, implement and evaluate multifaceted research projects involving mouse models of neurological diseases:
- Plan, schedule, and implement breeding of experimental cohorts taking into account behavioral or neurological phenotypes with a known temporal progression, in order to achieve sufficient animal numbers (including statistical power calculations), include sufficient controls and satisfy experimental designs.
- Coordinate time sensitive experimental procedures that require advanced planning with colleagues to ensure that behavioral and surgical rooms are available when needed and staff are available.
- Perform mouse husbandry, stereotaxic surgery, behavioral testing and drug delivery on mouse models of neurological diseases.
- Maintain tissue and animal databases and generate new tissue inventories for all managed experiments
- Provide tissue and animals to other staff members or collaborators at the UMN or other institutions, including the proper documentation, safe and appropriate packaging of biological samples, preparation of shipments and communication with the recipient investigators.

35% Design, plan, implement and evaluate research projects involving protein studies of neurological diseases:
- Design, plan and implement studies of human and mouse brain tissue, CSF and blood to look for biomarkers of AD and other neurological diseases using Quanterix SIMOA.
- Evaluate the validity of results and troubleshoot assays and/or experimental designs as necessary to improve outcomes.
- Perform protein extractions, immunoprecipitation, Western blots and other procedures as needed to meet experimental designs.

15% Laboratory Administration:
- Supervise controlled substance usage and DEA records; including ordering, proper storage and dosages, and disposal of controlled substances
- Serve as main point of contact for Laboratory Safety and ensure new and existing lab staff are properly trained and receive yearly updates. Serve as primary designate for DEHS and disposal of hazardous waste.
- Troubleshooting a wide range of technical issues within the lab, including computer hardware or software issues, analytical equipment (eg. real time light cycler, thermalcycler), and behavioral equipment. Troubleshooting and/or working with vendor's technical support, maintaining and upgrading critical infrastructure to prevent downtime or loss of experiments.
- Develop or alter standard operating procedures when necessary
- Regular attendance of lab meetings and seminars, including presentation of data and provide updates on current and planned experiments, provide feedback and critical assessment of data presented by other team members.
- Assist with writing papers and preparing data for grant applications and other funding opportunities

Required Qualifications:
- Advance degree with at least 1 year of relevant experience
- Must have experience handling animal models

Preferred Qualifications:
- Experience with stereotaxic surgery and/or animal behavior testing
- Demonstrate working knowledge/troubleshooting of computer hardware
- Experience with Quanterix SIMOA or other sophisticated assay platform
- Experience with statistical and graphing software (ie. Graphpad, SAS, SPSS) Molecular biology experience (cloning, transformation, bioinformatics)
- Cell culture experience

Working at the University

At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.

The University also offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF)
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• with free or reduced rates in the Twin Cities metro area

Please visit the for more information regarding benefits.

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U:

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).