Postdoctoral position available for highly motivated candidate in the Levinson Laboratory in the Department of Pharmacology at the University of Minnesota, Twin Cities campus. The Levinson Lab studies allostery and drug recognition in protein kinases using advanced biophysical spectroscopy coupled with structural and biochemical methods. A core focus of the lab is understanding the allosteric basis for how drug binding to the active site modulates kinase protein-protein interactions in cancer. Our projects are performed in close collaboration with the lab of David D. Thomas in the Department of Biochemistry, Molecular Biology, and Biophysics, whose instrumentation for time-resolved fluorescence and magnetic resonance forms a core component of our experimental toolkit. Successful applicants will have a PhD degree in Chemistry with experience in advanced biophysical spectroscopy including electron paramagnetic resonance and will work in a highly collaborative environment that spans the disciplines of structural biology and biophysics. Primary duties include:

75% experimental work to lead a project(s) in the lab.

• Real-time tracking of ligand-driven allosteric structural transitions in kinases using time-resolved FRET and EPR
• Dissection of oncogenic kinase scaffolding interactions using X-ray crystallography, cryo-EM, NMR, EPR and FRET
• Allosteric drug discovery using a novel high-throughput screening platform based on nanosecond time-resolved FRET
  

15% publication and presentation of data

• Maintaining accurate records
• Communicating findings through publications in peer-reviewed journals
• Preparing and giving presentations at local and national meetings
  

10% training of lab personnel

• Contributing to the training of junior personnel (undergraduate and graduate students, technicians) in the lab
• Fostering a safe, collegial, and inclusive workplace environment

Required Qualifications
* PhD in Chemistry
* Training in biophysical spectroscopy including electron paramagnetic resonance
* Strong communication and interpersonal skills
* Aptitude for working in a collaborative team

Preferred Qualifications
* Experience with recombinant protein expression, particularly in insect cells and/or mammalian cells

Working at the University

At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.

The University also offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Public Service Loan Forgiveness (PSLF)
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• with free or reduced rates in the Twin Cities metro area

Please visit the for more information regarding benefits.

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-UOHR (8647).

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U:

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).