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The Therapy Modeling and Design Center (TMDC), a new University of Minnesota research center, seeks to hire up to three Post-Doctoral researchers to lead multiple projects under the mission of the TMDC which is to leverage mechanistic mathematical modeling and engineering principles to optimize therapy designs. More information about the center can be found here: .
The successful candidate will be responsible for leading TMDC modeling projects focused on developing multiscale computational models that advance the development of cancer therapies (e.g. cell-based therapies, small molecules, radiation, etc.) through close collaboration with therapy developers, experimentalists, and clinical trialists.
All TMDC personnel will be expected to be present on campus for weekly core center activities and meetings, but will also have the option of a hybrid work schedule. TMDC is closely connected to the UMN Cancer Bioengineering Initiative and TMDC post-docs will have many opportunities to interact with this community which includes > 60 graduate students and post-docs. In addition, TMDC is supported by the Masonic Comprehensive Cancer Center and the College of Science & Engineering, which provide additional opportunities for seminars and symposia. The position has secure funding for three years and strong prospects for future funding through grant writing and philanthropy efforts already in motion. The salary range is $60k - 70K, depending on qualifications and experience. TMDC is committed to establishing a diverse, equitable, and inclusive culture and the successful applicant will be expected to help develop and implement center policies and practices to this end.
Major Responsibilities:20% - Develop novel theoretical models of biological processes driving therapy response, working closely with therapy developers, TMDC directors, and additional collaborators with relevant subject area expertise.
20% - Convert theoretical models to mathematical models using appropriate modeling strategies. Parametrize models using experimental data, simulate models (using MatLab, C++, Python, or other suitable programming language) and perform sensitivity analyses.
20% - Utilize mathematical models to optimize and improve therapy development process (e.g. design dosing regimens, minimize toxicities, identify combination therapy and synergy opportunities).
15% Analyze modeling results and present to TMDC Modeling Team including Directors, and Therapy Developer collaborators
15% - Develop and document process and results in internal reports and manuscripts submitted for publication in peer-reviewed archival scientific journals
5% - Meet with therapy developers and experimental collaborators on an as-needed basis to discuss relevant biological theory, review literature, and discuss model development and results.
5% - Develop and manage project schedules to ensure timely completion of project deliverables
Required Qualifications:
- Ph.D. in engineering, math, physical sciences, or related field, with life sciences knowledge
- Math modeling experience including numerical solution approaches
- Growth mindset / willing to learn new things
- Strong publication record
- Demonstrated potential for leading a research group and managing multiple projects
Preferred Qualifications:
- Clinical trials experience / knowledge PK/PD modeling
- Knowledge of differential equation and agent-based modeling
- Cellular and molecular biology expertise
- Working knowledge of fundamental principles of physics and chemistry
- Demonstrated interest and accomplishment in advancing diversity, equity, and inclusion
- Working knowledge of statistics and machine learning including sensitivity analysis
The mission of the Therapy Modeling and Design Center (TMDC), a new UMN research center officially launching in the second half of 2023, is to leverage mechanistic mathematical modeling and engineering principles to optimize therapy designs. TMDC is closely connected to the UMN Cancer Bioengineering Initiative and TMDC post-docs will have many opportunities to interact with this community which includes > 60 graduate students and post-docs. In addition, TMDC is supported by the Masonic Comprehensive Cancer Center and the College of Science & Engineering, which provide additional opportunities for seminars and symposia.
Working at the University
At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.
The University also offers a comprehensive benefits package that includes:
- Competitive wages, paid holidays, and generous time off
- Continuous learning opportunities through professional training and degree-seeking programs supported by the
- Low-cost medical, dental, and pharmacy plans
- Healthcare and dependent care flexible spending accounts
- University HSA contributions
- Disability and employer-paid life insurance
- Employee wellbeing program
- Excellent retirement plans with employer contribution
- Public Service Loan Forgiveness (PSLF)
- Financial counseling services
- Employee Assistance Program with eight sessions of counseling at no cost
- with free or reduced rates in the Twin Cities metro area
Please visit the for more information regarding benefits.
Applications must be submitted online. To be considered for upcoming positions, please apply through . The preferred start date will be the summer of 2024. Applications will be reviewed starting December 1, 2023.
To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-UOHR (8647).
Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.
The University of Minnesota, Twin Cities (UMTC)
The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.
At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).
The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.
The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu.