Research and Development Intern * Drug Discovery
Maple Grove, MN 
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Posted 27 days ago
Job/Internship Description

Vyant Bio, a NASDAQ-listed biotechnology company, is reinventing drug discovery for complex neurodevelopmental and neurodegenerative brain disorders. Our CNS drug discovery platform combines human patient-derived organoid models of brain disease, biology at scale, and machine learning to i) elucidate disease pathophysiology; ii) formulate key therapeutic hypotheses; iii) identify and validate drug targets, cellular assays and clinically translatable biomarkers to guide candidate molecule selection; and iv) guide patient selection and clinical trial design.

We are seeking a highly motivated Computational Biologist to join our Data Science team within the R&D organization. This role will provide exposure to multiple phases of drug discovery and development, with a mission to leverage information-rich datasets to validate targets, elucidate mechanism of action, and inform patient selection strategy. The successful candidate will interact closely with colleagues across the company, and be a key contributor on a multidisciplinary, cross-site R&D team.

Scope: The Research and Development Intern will assist in day-to-day tasks related to the drug discovery and in-vitro screening efforts at our Maple Grove, MN facility. The ideal candidate will be a highly motivated, driven and team-oriented individual with a solid understanding of biology, neuroscience, or related fields.

RESPONSIBILITIES

  • Culture, expand, and passage mammalian stem cells, iPSCs, and neural co-cultures
  • Maintain patient-derived brain organoid cultures for platform development, disease phenotyping, and drug screening
  • Conduct media changes and compound dosing using manual and automated equipment
  • Prepare biological reagents and buffers, aliquot biological samples, autoclave samples, conduct routine lab maintenance and cleaning
  • Support data and statistical analysis using diverse software suites (Microsoft office, GraphPad Prism, JMP)
  • Create and maintain experimental documentation
  • Participate in and lead journal club discussions related to our key research areas
  • Support cross-site and cross-functional drug discovery core team research and data analysis

EXPERIENCE & EDUCATION REQUIREMENTS

  • Working towards a degree in Biology, Biochemistry, or related field currently completing sophomore or junior year
  • Familiarity with basic research techniques such as flow cytometry, immunofluorescence, bioassays, or microscopy.

REQUIRED SKILLS AND ABILITIES

  • Ability to follow complex instructions and carry out tasks.
  • Works a minimum of 30+ hours per week during the summer.
  • Desire to work with human derived stem cells using aseptic technique.
  • Ability to follow Good Laboratory/Documentation Practices and complete paperwork.
  • Flexible and willing to perform a variety of tasks to meet the needs of the business.
  • Must be detail oriented with strong verbal communication, interpersonal and problem-solving skills.
  • Great work ethic with potential for long-term employment.
  • Ability to be flexible to the time requirements of working with living cells. This includes possible work on holidays and weekends as needed.

Equal Opportunity / Affirmative Action Employer

 

Position Summary
Start Date
As soon as possible
Employment Type
Full Time
Period of Employment
Open
Type of Compensation
Paid
College Credits Earned
No
Tuition Assistance
No
Required Student Status
Open
Preferred Majors
Other
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